Found 17 matching trials
A Phase IIa. Open-label, Multicenter, Dose-escalation Study to Assess the Tolerability and Pharmacokinetics of ZD4054 (Zibotentan) Given Orally Once Daily in Subjects With Metastatic Prostate Cancer PHASE2 The primary purpose of this study is to determine the safest dose of ZD4054...
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Food Effect Study of a Single Dose of ZD4054 (Zibotentan) PHASE1 The purpose of the study is to assess the effect of food on the pharmacokin...
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Zibotentan, an Endothelin Receptor Antagonist, Patients With Intermittent Claudication PHASE2 Peripheral artery disease (PAD) is a major complication of atherosclerosis ...
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University Of Virginia Health System
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10mg ZD4054 (Zibotentan) PK Study in Male, Elderly Chinese Patients With Advanced Solid Malignancies PHASE1 The purpose of this study is to assess the pharmacokinetics of single and m...
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ZD4054 (Zibotentan) in Pain-free or Mildly Symptomatic Patients With Prostate Cancer and Bone Metastases Who Have Rising Serum Prostate Specific Antigen (PSA) PHASE2 This study is being carried out to see if ZD4054 (Zibotentan) is effective ...
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Pharmacokinetics, Safety & Tolerability of ZD4054 (Zibotentan) in Subjects With Normal, Mild, Moderate and Severe Hepatic Impairment PHASE1 This study is designed to compare how ZD4054 (Zibotentan) is taken up, how ...
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ZD4054 (Zibotentan) or Placebo Plus Chemotherapy in Patients With Advanced Ovarian Cancer PHASE2 The purpose of this study is to compare progression-free survival in patien...
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A Phase IIb Study to Evaluate the Safety of Zibotentan/Dapagliflozin in Participants With Cirrhosis-ZEAL-UNLOCK PHASE2 This is a Phase IIb multicentre, randomised, double-blind, parallel-group, ...
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Zibotentan and Dapagliflozin for the Treatment of CKD (ZENITH-CKD Trial) PHASE2 The purpose of the study is to assess efficacy, safety and tolerability of ...
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Zibotentan and Dapagliflozin in Patients With Type 2 Diabetes and Elevated Albuminuria PHASE2 The aim of this study is to test the hypothesis that the effects on albumin...
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Anschutz Medical Campus
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